Beilstein J. Org. Chem.2019,15, 1505–1514, doi:10.3762/bjoc.15.152
Piyali Sarkar Sayan Sarkar Pradyut Ghosh School of Chemical Sciences, Indian Association for the Cultivation of Science, 2A & 2B Raja S.C Mullick Road, Kolkata-700032, India 10.3762/bjoc.15.152 Abstract A heteroditopicmacrocycle is reported as an efficient organocatalytic nanoreactor for the
synthesis of diversely functionalized pyrroloacridinones in aqueous medium. A library of compounds was synthesized in a one-step pathway utilizing 10 mol % of the nanoreactor following a sustainable methodology in water with high yields.
Keywords: heteroditopicmacrocycle; organocatalyst; nanoreactor
summary, a multifunctional heteroditopicmacrocycle is established as an efficient nanoreactor for organic transformations in water. Using this macrocycle, a library of biologically interesting highly substituted pyrroloacridines has been synthesized with high yields from easily available starting